The first phase is called an acute phase lasting from one to two weeks. The characteristics and symptoms that may be shown by children affected by this disease: fever over 39 degrees C and lasts for five days or more, red eye (conjunctivitis) without any dirt, red hay fever rash on body parts and genital parts, lips swollen, red, dry, cracked, tongue swelling and red (strawberry tongue), the palms of the hands and feet are swollen and red in color, swelling of mucous membranes in the neck. The symptoms shown in this first phase are somewhat similar to other diseases, such as fever, measles, allergies, or thyroid disease (parotitis).
Many parents think that their child has a common fever, so they give acetaminophen or ibuprofen to relieve fever in children. However, fever in children suffering from Kawasaki disease will not be responsive to antibiotics or antibiotics. In addition, the administration of drugs may also interfere with the measurement of how severe and how long the duration of fever the child, which will be used for further diagnosis by the physician concerned. Diagnosis should be done in this phase.
The next phase is referred to as the sub-acute phase, which can occur until the sixth week. Visible traits: peeling the skin of the hands and feet, especially on the fingertips, joint pain, diarrhea, gag, loss of appetite, pain in the abdominal. In this phase, there is an increase in the number of platelets in the body that can exceed 1 million / μL of blood (thrombocytosis) and the development of coronary aneurysms. If in this phase the child is still fever, the risk of heart complications is increasing. The risk of sudden death also increased dramatically in this phase.
In the third phase of the healing phase, signs and symptoms slowly begin to disappear, unless the complication of the disease is worse. After one to two months from the fever, a horizontal transverse line appears on the nails of the hands and feet, known as the Beau’s lines, due to a disease affecting the whole body. In the healing phase, cardiac abnormalities may still exist.
The chronic phase only occurs in patients with severe heart complications. This can usually continue into adulthood, given the clogging of blood vessels that formed in childhood can break apart in adulthood. Other possible complications include cardiac inflammation of the heart (myocarditis), pericardial inflammation (pericarditis), abnormal heart rate (arrhythmia), enlargement of heart size (cardiomegaly), to heart valve disorders that cause blood to flow from the left ventricle to the atrium left (mitral regurgitation).